Monoacylglycerol Lipase Inhibitor, URB602 is a cell-permeable N-biphenyl carbamate compound that has been found to act as a non-competitive and selective inhibior of Monoglyceride Lipase (monoacylglycerol lipase, MAGL). Monoacylglycerol Lipase Inhibitor, URB602 has not been found to inhibit FAAH, COX-2, or diacylglycerol lipase activity. Monoacylglycerol Lipase Inhibitor, URB602 has been shown to increase antinociception induced by stress, most likely through increasing 2-arachidonylglycerol levels.
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