MMP Inhibitor V is used for testing effective treatment of MMP-related diseases. MMP Inhibitor V, also called ONO-4817 is a cell permeable non-peptidyl hydroxamate compound that acts as an effective broad-spectrum inhibitor against MMP-2/3/8/9/12/13, but not MMP-1, MMP-7, or other serine proteases. Widely used in studying MMP-mediated disease development. Also reported to block P-LAP secretase activity that is otherwise not inhibited by TIMP-1/2 in CHO cell cultures in vitro.
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