Anti-MMP-3/10 Antibody (F-10) is a mouse monoclonal IgG1 κ MMP-3/10 antibody, cited in 3 publications, provided at 200 µg/ml
raised against amino acids 178-477 mapping at the C-terminus of MMP-3 of human origin
Anti-MMP-3/10 Antibody (F-10) is recommended for detection of MMP-3 and MMP-10 of mouse, rat and human origin by WB, IP, IF and ELISA; may cross-react with other MMP family members
Anti-MMP-3/10 Antibody (F-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of MMP-3/10 (F-10): sc-374029.
m-IgG Fc BP-HRP (mouse IgG Fc binding protein-HRP) and m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) are the preferred secondary detection reagents for MMP-3/10 Antibody (F-10) for WB applications. These reagents are now offered in bundles with MMP-3/10 Antibody (F-10) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
MMP-3/10 Antibody (F-10) is a high quality monoclonal MMP-3/10 antibody (also designated MMP3/10 antibody) suitable for the detection of the MMP-3/10 protein of mouse, rat and human origin. MMP-3/10 Antibody (F-10) is available as both the non-conjugated anti-MMP-3/10 antibody form, as well as multiple conjugated forms of anti-MMP-3/10 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, -2 and -3 respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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