Mitotane, or o,p'-DDD, is a derivative of DDT (sc-238975) with antiproliferative properties. A study of the antiproliferative effects of Mitotane demonstrated particular efficacy against adrenocortical carcinoma.
1. Haq, M.M., et al. 1980. Cancer Treat Rep. 64: 909-913. PMID: 7448828 2. Luton, J.P., et al. 1990. N. Engl. J. Med. 322: 1195-1201. PMID: 2325710
Soluble in DMSO (≥ 64 mg/ml), ethanol (≥ 64 mg/ml), and water (< 1 mg/ml).
Store at room temperature
75-81° C (lit.)
398.88° C at 760 mmHg (Predicted)
1.37 g/cm3 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Mitotane Product Citations
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Rated 5 out of
Luton et alLuton et al. (PubMed ID 2325710) showed that mitotane is an adrenal cytotoxic agent that controls hormonal secretions in adrenocortical carcinoma and could be used to mitigate endocrine symptoms without having a significant effect on survivability. -SCBT Publication Review
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