Date published: 2025-10-14

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Methyl trans-cinnamate (CAS 1754-62-7)

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Alternate Names:
Methyl (E)-3-phenylprop-2-enoate
Application:
Methyl trans-cinnamate is an antimicrobial
CAS Number:
1754-62-7
Purity:
≥99%
Molecular Weight:
162.19
Molecular Formula:
C10H10O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methyl trans-cinnamate is a compound that dissolves well in alcohols, ether, and benzene, but has limited solubility in water. It acts as an inhibitor of the c. glabrata polymerase chain reaction by binding to the enzyme and curbing its catalytic function, thereby hindering DNA synthesis. The compound also exhibits notable thermal expansion characteristics, making it suitable for inclusion in polymeric materials like polyurethanes, polyesters, and polyamides. In scientific research, Methyl trans-cinnamate serves multiple roles, including as a precursor for synthesizing other chemicals and as a standard reference substance in analytical chemistry. Methyl trans-cinnamate can be used to inhibit monophenolase and diphenolase activity of mushroom tyrosinase. It has antimicrobial activity.


Methyl trans-cinnamate (CAS 1754-62-7) References

  1. Inhibitory effects of methyl trans-cinnamate on mushroom tyrosinase and its antimicrobial activities.  |  Huang, QS., et al. 2009. J Agric Food Chem. 57: 2565-9. PMID: 19231901
  2. A Method for Converting HPLC Peak Area from Online Reaction Monitoring to Concentration Using Nonlinear Regression.  |  Deem, MC. and Hein, JE. 2023. J Org Chem. 88: 1292-1297. PMID: 36625157
  3. Structure-Activity Relationship (SAR) Study of trans-Cinnamic Acid and Derivatives on the Parasitic Weed Cuscuta campestris.  |  Moreno-Robles, A., et al. 2023. Plants (Basel). 12: PMID: 36840045
  4. Molecular Aspects of the Functioning of Pathogenic Bacteria Biofilm Based on Quorum Sensing (QS) Signal-Response System and Innovative Non-Antibiotic Strategies for Their Elimination.  |  Juszczuk-Kubiak, E. 2024. Int J Mol Sci. 25: PMID: 38473900
  5. Antimicrobial activity of essential oils against biofilms formed in dental acrylic resin: a systematic review of in vitro studies.  |  Carvalho-Silva, JM., et al. 2024. Biofouling. 40: 114-129. PMID: 38538551
  6. cis-trans Photoisomerization in Tri-Ortho-Thymotide Inclusion Complexes: Crystal Structures of cis- and trans- Stilbene TOT Clathrates  |  R. Arad-yellin, et al. 1979. Molecular Crystals and Liquid Crystals. 50(1): 275-277.
  7. Hydrogen bonding involving α, β-unsaturated carboxylic esters and substituted phenols: an infrared spectroscopic study  |  Faria, M. D. G., Teixeira-Dias, J. J. C., & Fausto, R. 1991. Journal of molecular structure. 263: 87-94.
  8. An Undergraduate Organic Chemistry Laboratory: The Facile Hydrogenation of Methyl trans-Cinnamate  |  Kenneth J. O'Connor, Kimberly Zuspan, and Lonnie Berry. 2011. J. Chem. Educ. 88(3): 325–327.
  9. Chemistry Education Fostering Creativity in the Digital Era  |   and Dr. Mario Pagliaro. 2019. Israel Journal of Chemistry. 59(6-7): 565-571.
  10. Chemical Composition of Essential Oils Extracted from the Leaves and Rhizomes of Alpinia hongiaoensis Tagane.(Zingiberaceae) growing Wild in Vietnam  |  Trung, H. T., Giang, L. D., Thuan, V. T., Van Trung, H., Hieu, N. N., Duc, N. D.,.. & Duc, D. X. 2023. Journal of Essential Oil Bearing Plants. 26(2): 396-402.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Methyl trans-cinnamate, 100 g

sc-228580
100 g
$28.00