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Methyl (S)-(+)-3-hydroxy-2-methylpropionate (CAS 80657-57-4)

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Alternate Names:
(+)-Methyl L-β-hydroxyisobutyrate; (S)-(+)-3-Hydroxy-2-methylpropionic acid methyl ester
CAS Number:
80657-57-4
Molecular Weight:
118.13
Molecular Formula:
C5H10O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methyl (S)-(+)-3-hydroxy-2-methylpropionate is a compound of interest in synthetic chemistry, particularly in the realm of asymmetric synthesis and chiral resolution studies. Its (S)-enantiomer configuration is useful for researchers looking to understand the influence of chirality on chemical reactions and physical properties. The compound serves as a chiral building block for the construction of more complex molecules, including natural products and active pharmaceutical ingredients. Additionally, it acts as a model for studying enzymatic reactions that involve chiral molecules, contributing to the understanding of enzyme selectivity and specificity. Methyl (S)-(+)-3-hydroxy-2-methylpropionate is also employed in the preparation of chiral esters and alcohols, enabling chemists to explore the stereoselective transformations that are fundamental to the production of enantiomerically pure substances.


Methyl (S)-(+)-3-hydroxy-2-methylpropionate (CAS 80657-57-4) References

  1. Total synthesis of deschlorocallipeltoside A.  |  Trost, BM. and Gunzner, JL. 2001. J Am Chem Soc. 123: 9449-50. PMID: 11562231
  2. Applications of Crotonyldiisopinocampheylboranes in Synthesis: Total Synthesis of Restrictinol.  |  Barrett, AG., et al. 1999. J Org Chem. 64: 162-171. PMID: 11674099
  3. Total synthesis of polycavernoside A, a lethal toxin of the red alga Polycavernosa tsudai.  |  Blakemore, PR., et al. 2005. J Org Chem. 70: 5449-60. PMID: 15989326
  4. Characterization and immobilization of a novel SGNH hydrolase (Est24) from Sinorhizobium meliloti.  |  Bae, SY., et al. 2013. Appl Microbiol Biotechnol. 97: 1637-47. PMID: 22526795
  5. Novel biphenyl-substituted 1,2,4-oxadiazole ferroelectric liquid crystals: synthesis and characterization.  |  Subrao, M., et al. 2015. Beilstein J Org Chem. 11: 233-41. PMID: 25815075
  6. Improved Synthesis of the C8-C23 Segment of Aplysiatoxins via Asymmetric Dihydroxylation of the Chiral Homoallylic Alcohol.  |  Toshima, H. and Ichihara, A. 1998. Biosci Biotechnol Biochem. 62: 599-602. PMID: 27315938
  7. Simple Synthesis of Both Enantiomers of the C7-C12 Segment of Epothilones.  |  Tanimori, S., et al. 1998. Biosci Biotechnol Biochem. 62: 2428-30. PMID: 27392400
  8. Crystal Structure and Functional Characterization of an Esterase (EaEST) from Exiguobacterium antarcticum.  |  Lee, CW., et al. 2017. PLoS One. 12: e0169540. PMID: 28125606
  9. [Total synthesis of antitumor macrolide, rhizoxin and chemistry of acylsilane].  |  Nakada, M. 1997. Yakugaku Zasshi. 117: 486-508. PMID: 9306725

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Methyl (S)-(+)-3-hydroxy-2-methylpropionate, 5 g

sc-250329
5 g
$189.00