Methyl 2-Deoxy-2-N-phthalimido-β-D-glucopyranoside (CAS 76101-14-9)

Methyl 2-Deoxy-2-N-phthalimido-β-D-glucopyranoside is a synthetic derivative of glucose commonly used in biochemical research to investigate carbohydrate chemistry and glycobiology. Its structure, featuring a phthalimide group at the 2-position and a 2-deoxy modification, allows for versatile applications. This compound serves as a valuable substrate for studying enzymatic processes involving glycosidic bond cleavage and synthesis. Specifically, it is utilized as a glycosyl donor or acceptor in glycosylation reactions catalyzed by glycosyltransferases. Researchers often employ it to probe the substrate specificity, kinetics, and mechanisms of various glycosyltransferase enzymes, shedding light on their roles in cellular processes such as protein glycosylation, signal transduction, and cell-cell recognition. Moreover, Methyl 2-Deoxy-2-N-phthalimido-β-D-glucopyranoside serves as a precursor for the synthesis of complex glycoconjugates, including glycopeptides and glycolipids, facilitating the study of their biological functions and interactions. Its versatility and synthetic accessibility make it a valuable tool for advancing our understanding of carbohydrate-mediated processes in both normal physiology and disease states, contributing to the broader field of glycobiology.