Methoxyacetyl chloride (CAS 38870-89-2)
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Methoxyacetyl chloride functions as an acetylating agent in organic synthesis. It is used to introduce the methoxyacetyl protecting group into various organic molecules, particularly in the preparation of agrochemicals. The mechanism of action involves the reaction of methoxyacetyl chloride with hydroxyl or amino groups in the target molecule, resulting in the formation of an acetyl ester or amide. This process effectively protects these functional groups from undesired reactions during subsequent synthesis steps. Methoxyacetyl chloride′s role in the acetylation of hydroxyl and amino groups is useful for the successful synthesis of complex organic compounds, allowing for the precise manipulation of molecular structures without interference from other reactive groups.
Methoxyacetyl chloride (CAS 38870-89-2) References
- Electrophilic Aromatic Substitution. 13.(1) Kinetics and Spectroscopy of the Chloromethylation of Benzene and Toluene with Methoxyacetyl Chloride or Chloromethyl Methyl Ether and Aluminum Chloride in Nitromethane or Tin Tetrachloride in Dichloromethane. The Methoxymethyl Cation as a Remarkably Selective Common Electrophile. | DeHaan, FP., et al. 1997. J Org Chem. 62: 2694-2703. PMID: 11671627
- Construction of an advanced tetracyclic intermediate for total synthesis of the marine alkaloid sarain A. | Hong, S., et al. 2006. J Org Chem. 71: 2078-89. PMID: 16496996
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Methoxyacetyl chloride, 5 g | sc-250321 | 5 g | $20.00 |