Meta Fluoxetine HydrochlorideAn isomer and impurity of Fluoxetine

Meta Fluoxetine Hydrochloride (CAS 79088-29-2)

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Application: An isomer and impurity of Fluoxetine
CAS Number: 79088-29-2
Purity: ≥97%
Molecular Weight: 345.79
Molecular Formula: C17H19ClF3NO
* Refer to Certificate of Analysis for lot specific data (including water content).
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Meta Fluoxetine Hydrochloride is an isomer and impurity of Fluoxetine. Fluoxetine is a 5-hydroxytryptamine (serotonin, 5-HT) reuptake inhibitor. This compound is a racemic mixture and both R and S enantiomers are reported to inhibit 5-HT uptake in synaptosomal preparations of rat cerebral cortex. Fluoxetine is also noted to be a highly selective, sodium dependent, 5-HT transporter in studies of rat cerebrums. Additionally, Fluoxetine is also noted to increase extracellular levels of 5-HT in several areas of the rat brain as a result of reuptake inhibition. This increase in availability of 5-HT is reported to lead to a decrease in synthesis and turnover of 5-HT. Other available forms include (R)-Fluoxetine (sc-208240) and (S)-Fluoxetine Hydrochloride (sc-208367). Deuterium-labeled (S)-Fluoxetine-d5 Hydrochloride (sc-220069) and (R)-Fluoxetine-d5 Hydrochloride (sc-219754).


References

1. Wong, D.T., et al. 1995. Life Sci. 57: 411-441. PMID: 7623609
2. Beck, S.G., et al. 1997. J. Pharmacol. Exp. Ther. 281: 115-122. PMID: 9103487
3. Owens, M.J., et al. 1997. J. Pharmacol. Exp. Ther. 283: 1305-1322. PMID: 9400006

Physical State :
Solid
Solubility :
Soluble in MeOH, DMSO, and DMF
Storage :
Store at room temperature
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
57369875
SMILES :
CNCCC(C1=CC=CC=C1)OC2=CC=CC(=C2)C(F)(F)F.Cl

Download SDS (MSDS)

Certificate of Analysis

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