MertansineA cytotoxic agent used in antibody-drug conjugates

Mertansine (CAS 139504-50-0)

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Synonym: DM 1; Maytansinoid DM 1
Application: A cytotoxic agent used in antibody-drug conjugates
CAS Number: 139504-50-0
Molecular Weight: 738.29
Molecular Formula: C35H48ClN3O10S
* Refer to Certificate of Analysis for lot specific data (including water content).
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Physical State :
Solid
Storage :
Store at -20° C
Melting Point :
178-180° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
71301226
SMILES :
C[C@@H]1[C@@H]2C[C@]([C@@H](/C=C\C=C(\CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@H]([C@]4(C1O4)C)OC(=O)[C@H](C)N(C)C(=O)CCS)C)/C)OC)(NC(=O)O2)O

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What is the extinction coefficient of Mertansine in DMSO?

Asked by: yaa2754
We would not recommend storing this material in solution for any extended period of time. Once dissolved, it should be used right away to avoid decomposition in solution over time.
Answered by: Technical Support
Date published: 2019-04-13
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