Meropenem Trihydrate (CAS 119478-56-7)
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Meropenem trihydrate is a highly potent form of meropenem, a synthetic broad-spectrum carbapenem antibiotic, that has been extensively used in microbiological research to study bacterial resistance mechanisms and the efficacy of antibacterial treatments. It works by inhibiting bacterial cell wall synthesis, a process for bacterial growth and replication, through binding to penicillin-binding proteins (PBPs). This binding leads to the disruption of cell wall structure, resulting in bacterial cell death. Meropenem trihydrate is particularly valued in research due to its stability and ability to act against a wide range of Gram-positive and Gram-negative bacteria. This makes it an ideal candidate for use in experimental applications that examine the interactions between antibiotics and bacterial pathogens, helping to elucidate the pathways of resistance and the potential for new antibacterial strategies. Its role in the study of microbial ecology and the development of novel antibacterial agents continues to be a cornerstone in microbiological research, contributing to a deeper understanding of microbial dynamics and resistance patterns.
Meropenem Trihydrate (CAS 119478-56-7) References
- Comparing outcomes of meropenem administration strategies based on pharmacokinetic and pharmacodynamic principles: a qualitative systematic review. | Perrott, J., et al. 2010. Ann Pharmacother. 44: 557-64. PMID: 20124468
- Life-years gained with meropenem over ciprofloxacin in penicillin-allergic patients with gram-negative bacilli sepsis: results of a probabilistic model. | Scheetz, MH., et al. 2011. Pharmacotherapy. 31: 469-79. PMID: 21923428
- [Meropenem--therapeutic recommendation after twenty years of presence on pharmaceutical market]. | Paczkowska, M., et al. 2014. Postepy Hig Med Dosw (Online). 68: 441-5. PMID: 24864096
- Sepsis caused by New Delhi metallo-β-lactamase (blaNDM-1) and qnrD-producing Morganella morganii, treated successfully with fosfomycin and meropenem: case report and literature review. | Seija, V., et al. 2015. Int J Infect Dis. 30: 20-6. PMID: 25447717
- A Review of Clinical Outcomes Associated with Two Meropenem Dosing Strategies. | Wilby, KJ., et al. 2017. Drugs R D. 17: 73-78. PMID: 28101836
- Imipenem-Relebactam and Meropenem-Vaborbactam: Two Novel Carbapenem-β-Lactamase Inhibitor Combinations. | Zhanel, GG., et al. 2018. Drugs. 78: 65-98. PMID: 29230684
- Meropenem and Vaborbactam: Stepping up the Battle against Carbapenem-resistant Enterobacteriaceae. | Jorgensen, SCJ. and Rybak, MJ. 2018. Pharmacotherapy. 38: 444-461. PMID: 29427523
- Meropenem/Vaborbactam, the First Carbapenem/β-Lactamase Inhibitor Combination. | Cho, JC., et al. 2018. Ann Pharmacother. 52: 769-779. PMID: 29514462
- Meropenem-vaborbactam: a carbapenem and beta-lactamase inhibitor with activity against carbapenem-resistant Enterobacteriaceae. | Lee, YR. and Baker, NT. 2018. Eur J Clin Microbiol Infect Dis. 37: 1411-1419. PMID: 29675787
- Clinical outcomes of prolonged infusion (extended infusion or continuous infusion) versus intermittent bolus of meropenem in severe infection: A meta-analysis. | Yu, Z., et al. 2018. PLoS One. 13: e0201667. PMID: 30059536
- Pharmacokinetic evaluation of meropenem and vaborbactam for the treatment of urinary tract infection. | Burgos, RM., et al. 2018. Expert Opin Drug Metab Toxicol. 14: 1007-1021. PMID: 30106599
- Meropenem/Vaborbactam: A Review in Complicated Urinary Tract Infections. | Dhillon, S. 2018. Drugs. 78: 1259-1270. PMID: 30128699
- Meropenem-vaborbactam for the treatment of complicated urinary tract infections including acute pyelonephritis. | Wu, G. and Cheon, E. 2018. Expert Opin Pharmacother. 19: 1495-1502. PMID: 30160990
- Overview of meropenem-vaborbactam and newer antimicrobial agents for the treatment of carbapenem-resistant Enterobacteriaceae. | Petty, LA., et al. 2018. Infect Drug Resist. 11: 1461-1472. PMID: 30254477
- A Brief Review of a New Antibiotic: Meropenem-vaborbactam. | Gibson, B. 2019. Sr Care Pharm. 34: 187-191. PMID: 31155025
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Meropenem Trihydrate, 1 g | sc-485799 | 1 g | $224.00 |