Meloxicam sodium salt hydrate has been shown to abolish thymulin-induced increases of cytokines and NGF in the liver of rats and displays tumor growth suppression. Meloxicam may be capable of antagonizing cachexia in vitro. Meloxicam is a non-steroidal anti-inflammatory drug (NSAID) that shows 300-fold selectivity for Cox-2 (cyclooxygenase-2) inhibition versus Cox-1(cyclooxygenase-1) inhibition.
Hussey, H.J., Tisdale, M.J., Effect of specific cyclooxygenase-2 inhibitor meloxicam on tumour growth and cachexia in a murine model. Int. J. Cancer 87, 95, (2000) Safieh-Garabedian, B., The role of cytokines and prostaglandin-E(2) in thymulin induced hyperalgesia. Neuropharmacology 39, 1653, (2000)
See how others have used Meloxicam sodium salt. Click on the entry to view the PubMed entry .
PMID: # 27904016 Miyamoto, A.|Aoyama, T.|Matsumoto, Y.| et al. 2017. Chem. Pharm. Bull. 65: 121-126.
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