MEL-1A/B-R Antibody (B-8) is a mouse monoclonal IgM κ, cited in 5 publications, provided at 200 µg/ml
raised against amino acids 161-280 mapping within an internal region of MEL-1A-R of human origin
recommended for detection of MEL-1A-R and MEL-1B-R of mouse, rat and human origin by WB, IP, IF and ELISA
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of MEL-1A/B-R (B-8): sc-398788.
m-IgGκ BP-HRP is the preferred secondary detection reagent for MEL-1A/B-R Antibody (B-8) for WB applications. This reagent is now offered in a bundle with MEL-1A/B-R Antibody (B-8) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Melatonin (Mel), a hormone secreted by the pineal gland, is expressed at night in response to the circadian clock (1,2). Melatonin is thought to be involved in regulating reproductive physiological development and the progression of sexual maturation, and it is also thought to play a role in tumorigenesis. The melatonin receptors, MEL-1A-R and MEL-1B-R, are members of the super-family of guanine nucleotide-binding regulatory protein (G protein)-coupled receptors. Signaling through the melatonin receptors inhibits adenylate cyclase and stimulates phospholipase Cb upon activation of pertussis toxin (PTX)-sensitive G proteins. MEL-1A-R may be involved in pacing the biological clock. However, both MEL-1A-R and MEL-1B-R are implicated in controlling cellular growth in response to melatonin.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.