Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Cells selected for resistance to a single cytotoxic drug may become cross-resistant to a broad range of drugs with different structures and cellular targets. This phenomenon is called multiple drug resistance (MDR). MDR proteins (Mdrs) are members of a highly conserved superfamily of ATP-binding cassette transport proteins. Mdr-1 is an apical transmembrane protein that is an integral part of the blood-brain barrier and functions as a drug-transport pump transporting a variety of drugs from the brain back into the blood. The Mdr-1 gene is known as ABCB1 and is located on human chromosome 7. The mouse homolog of Mdr-1 is known as Mdr-3. Interestingly, a murine protein by the name of Mdr-1 exists and is encoded by the murine Abcb1b gene, but it is not homologous with human Mdr-1.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Can Mdr-1 (UIC2): sc-73354 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?
Asked by: jerojero
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, Mdr-1 (UIC2): sc-73354 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Rated 5 out of
Well established Mdr-1 monoclonal antibodyWith 9 citations in the primary literature this Mdr-1 monoclonal antibody is well liked and good characterized for the use in IP, IF, IHC(P), FCM in sevaral human samples.
Date published: 2017-01-31
Rated 4 out of
IHC publishable data on human breast tissueIHC publishable data on human breast tissue - SCBT Publication Review
Date published: 2015-01-30
Rated 4 out of
This antibody was used for IF (pfa) with human MCFThis antibody was used for IF (pfa) with human MCF-7DOX-2, MCF-7EPI and MCF-7TAX-2 cells - SCBT Publication Review
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn
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