MCP-2 CRISPR Plasmids (m) mouse MCP-2-specific CRISPR/Cas9 KO Plasmid, HDR Plasmid, Double Nickase Plasmids, CRISPR Activation Plasmids and Lentiviral Activation Particles

MCP-2 CRISPR Plasmids (m)

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    • Target species: mouse; for corresponding human product, see MCP-2 CRISPR Plasmids (h)
    • CRISPR/Cas9 KO Plasmids consists of MCP-2-specific 20 nt guide RNA sequences derived from the GeCKO (v2) library
    • For CRISPR gene knockout, gRNA sequences direct the Cas9 protein to induce a site-specific double strand break (DSB) in the genomic DNA
    • Target-specific CRISPR Plasmids for both gene knockout and activation are available. Please refer to the detailed product information in the tabs below
    • All products are provided as transfection-ready, purified plasmid DNA, except the Lentiviral Activation Particles which have been prepackaged as Lentiviral Particles for use with hard-to-transfect cells

Gene Info

SpeciesGene NameGene IDChromosome LocationIsoform (mRNA) Accession #Protein Accession #OMIM™ Number
MouseCcl82030711 CNM_021443Q9Z121N/A

Quiero utilizar el sistema de silenciamiento CRISPR/Cas9, para el gen "CCL8/MCP2" murino en modelo de ratón (in vivo) y posteriormente in vitro. ¿Qué necesitaría exactamente? ¿Cuál sería el presupuesto? :)

Asked by: ElenaFJD
Gracias por su pregunta. Nosotros no recomendamos ni respaldamos el uso de nuestros reactivos CRISPR para aplicaciones in vivo. Se recomiendan solo para uso in vitro. Para obtener información sobre qué otros productos de soporte son necesarios, contacte nuestro Departamento de Servicio Técnico . Thank you for your question. We do not recommend nor support the use of our CRISPR reagents for in vivo applications. They are recommended for in vitro use only. Please contact our Technical Service Department for information on what other support products are needed.
Answered by: Technical Support
Date published: 2019-09-11

What protein is this to? Three letter ACRONYMS make me a little nervous.

Asked by: Nat1
Thank you for your inquiry. Our MCP-2 CRISPR Knockout and Activation Products (m) are directed against the mouse gene with symbol Ccl8, gene ID 20307 on NCBI. This information can be found on the product page on our website under "Gene Info", as well as on the product datasheet(s). Below is a link out to the gene page on NCBI for your reference.
Answered by: Technical Support
Date published: 2016-11-10
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