MAP Kinase Antisense Oligonucleotide Negative ControlOligonucleotides are composed of well characterized consensus DNA sequences for specific transcription factors of interest. Mutant oligonucleotides are also available with one or more site-directed mutations for competitive gel shift assays.

MAP Kinase Antisense Oligonucleotide, Negative Control

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Application: A negative control with no effect on MAP kinase expression
Molecular Weight: 5200
* Refer to Certificate of Analysis for lot specific data (including water content).
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MAP Kinase Antisense Oligonucleotide, Negative Control is a 17-mer phosphorothioate oligodeoxynucleotide with the same nucleotide composition as the MAP kinase antisense oligonucleotide, but in a scrambled sequence. It does not have any effect on MAP kinase expression. Note: 25 nmol = 130 μg.


References

1. Sale, E M., et al., 1995. Requirement of MAP kinase for differentiation of fibroblasts to adipocytes, for insulin activation of p90 S6 kinase and for insulin or serum stimulation of DNA synthesis. The EMBO journal. 14(4): 674-84. PMID: 7882971
2. Robinson, C J., et al., 1996. Treatment of vascular smooth muscle cells with antisense phosphorothioate oligodeoxynucleotides directed against p42 and p44 mitogen-activated protein kinases abolishes DNA synthesis in response to platelet-derived growth factor. The Biochemical journal. 320 ( Pt 1)(): 123-7. PMID: 8947476

Appearance :
Lyophilized
Solubility :
Soluble in Water
Storage :
Store at -80° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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Certificate of Analysis

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