MAP Kinase Antisense Oligonucleotide, Negative Control is a 17-mer phosphorothioate oligodeoxynucleotide with the same nucleotide composition as the MAP kinase antisense oligonucleotide, but in a scrambled sequence. It does not have any effect on MAP kinase expression. Note: 25 nmol = 130 μg.
1. Sale, E M., et al., 1995. Requirement of MAP kinase for differentiation of fibroblasts to adipocytes, for insulin activation of p90 S6 kinase and for insulin or serum stimulation of DNA synthesis. The EMBO journal. 14(4): 674-84. PMID: 7882971
2. Robinson, C J., et al., 1996. Treatment of vascular smooth muscle cells with antisense phosphorothioate oligodeoxynucleotides directed against p42 and p44 mitogen-activated protein kinases abolishes DNA synthesis in response to platelet-derived growth factor. The Biochemical journal. 320 ( Pt 1)(): 123-7. PMID: 8947476
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