LXRα/β Antibody (G-10) is a mouse monoclonal IgG1 (kappa light chain) provided at 200 µg/ml
raised against amino acids 301-444 mapping near the C-terminus of LXRα
LXR alpha / beta Antibody (G-10) is recommended for detection of LXRα and LXRβ of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
LXR alpha / beta Antibody (G-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
TransCruz reagent for ChIP application (sc-271064 X, 200 µg/0.1 ml)
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of LXRα/β (G-10): sc-271064.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Retinoids are metabolites of vitamin A (retinol) and are believed to represent important signaling molecules during vertebrate development and tissue differentiation. The cooperation of liver X receptors (LXRs) α and β and retinoic X receptor (RXR) modulate the expression of several genes involved in lipid metabolism in hepatocyte and macrophages. RXR is the receptor for 9-cis retinoic acid and dimerizes with VDR, TR, PPAR and several novel receptors including liver X receptors LXRα (also referred to as RLD-1), LXRβ and FXR. FXR and LXR fall into a category of proteins termed "orphan receptors" because of their lack of a defined function, and in the case of LXR, the lack of a defined ligand. Both LXR/ RXR and FXR/RXR heterodimers retain their responsiveness to 9-cis retinoic acid. LXRα and LXRβ share considerable sequence homology and several functions, respond to the same endogenous and synthetic ligands and play critical roles in maintaining lipid homeostasis. LXRβ is ubiquitously expressed and enriched in tissues of neuronal and endocrine origin.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences