Lumefantrine is an antimalarial which inhibits hemozoin formation.
1. Kumar, N., et al., 1990. Stage-specific gametocytocidal effect in vitro of the antimalaria drug qinghaosu on Plasmodium falciparum. Parasitology research. 76(3): 214-8. PMID: 2179946 2. Chotivanich, K., et al., 2000. The mechanisms of parasite clearance after antimalarial treatment of Plasmodium falciparum malaria. The Journal of infectious diseases. 182(2): 629-33. PMID: 10915102 3. Mutabingwa, Theonest K., et al., . Amodiaquine alone, amodiaquine+sulfadoxine-pyrimethamine, amodiaquine+artesunate, and artemether-lumefantrine for outpatient treatment of malaria in Tanzanian children: a four-arm randomised effectiveness trial. Lancet. 365(9469): 1474-80. PMID: 15850631
Soluble in methanol, chloroform, DMSO (≥20 mg/ml), and water (slightly).
Store at room temperature
~642.5° C at 760 mmHg (Predicted)
~1.3 g/cm3 (Predicted)
n20D 1.63 (Predicted)
pKa: 13.44 (Predicted), pKb: 8.71 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Rated 5 out of
Mekonnen et alMekonnen et al. (PubMed ID 26271736) found that lumefantrine reduced gametocyte carriage Plasmodium falciparum, making it an effective treatment for malaria. -SCBT Publication Review
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