Lithium carbonate has been used in psychiatry since the 1950's to treat mania and depressive disorders. It is an element with a positive charge similar to sodium and potassium. In cells, lithium interferes with other positively charged atoms important to many cellular functions. It interferes with neurotransmitter production and uptake. Current biological studies are looking into lithium treatment for additional CNS disorders such as Alzheimer's disease.
1. Grandjean, E.M. and Aubry, J.M. 2009. CNS Drugs. 23: 331-349. PMID: 19374461 2. Leroy, K., et al. 2009. J. Alzheimers Dis. PMID: 19920318 3. Leroy, K., et al. 2010. J. Alzheimers Dis. 19: 705-719. PMID: 20110614
Crystalline or powder
Soluble in water (1.33 g in 100 mL at room temperature) and dilute acids. Insoluble in acetone and ethanol.
9.0 - 11.0 at 1 g/l
Store at room temperature
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Various publications cite the use of LithiumVarious publications cite the use of Lithium carbonate for interference of neurotransmission. -SCBT Publication Review
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