Lavendustin BA tyrosine kinase inhibitor

Lavendustin B (CAS 125697-91-8)

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Synonym: N,N-bis(2'-Hydroxybenzyl)-3-aminosalicylic acid
Application: A tyrosine kinase inhibitor
CAS Number: 125697-91-8
Purity: ≥97%
Molecular Weight: 365.4
Molecular Formula: C21H19NO5
* Refer to Certificate of Analysis for lot specific data (including water content).
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Lavendustin B is a weak tyrosine kinase inhibitor that has been used as a negative control for lavendustin A (sc-200539). Lavendustin A strongly inhibits epidermal growth factor receptor-associated tyrosine kinase, competes with ATP, and is noncompetitive with the peptide.


1. Onoda, T., et al. 1989. J. Nat. Prod. 52: 1252-1257. PMID: 2614420
2. Hu, D.E., et al. 1995. Br. J. Pharmacol. 114: 262-268. PMID: 7533611
3. Catarsi, S., et al. 1995. J. Physiol. 485: 775-786. PMID: 7562616
4. Meizel, S. and Turner, K.O. 1996. J. Androl. 17: 327-330. PMID: 8889693

Physical State :
Solubility :
Soluble in DMSO, ethanol (25 mg/ml), methanol, and dilute aqueous base.
Storage :
Store at -20° C
Melting Point :
189-190° C (lit.)
Boiling Point :
~671.11° C at 760 mmHg (Predicted)
Density :
~1.42 g/cm3 (Predicted)
Refractive Index :
n20D 1.73 (Predicted)
IC50 :
tyrosine kinase: IC50 = 1.3 µM; EGFR: IC50 = 1.37 µM (human)
pK Values :
pKa: 2.31 (Predicted), pKb: 4.23 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
MDL Number :

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Certificate of Analysis

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Lavendustin B  Product Citations

See how others have used Lavendustin B. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 8889693  Meizel, S. et al. 1996 Jul-Aug. J. Androl. 17: 327-330.

Citations 1 to 1 of 1 total
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