Lavendustin B is a weak tyrosine kinase inhibitor that has been used as a negative control for lavendustin A (sc-200539). Lavendustin A strongly inhibits epidermal growth factor receptor-associated tyrosine kinase, competes with ATP, and is noncompetitive with the peptide.
1. Onoda, T., et al. 1989. J. Nat. Prod. 52: 1252-1257. PMID: 2614420 2. Hu, D.E., et al. 1995. Br. J. Pharmacol. 114: 262-268. PMID: 7533611 3. Catarsi, S., et al. 1995. J. Physiol. 485: 775-786. PMID: 7562616 4. Meizel, S. and Turner, K.O. 1996. J. Androl. 17: 327-330. PMID: 8889693
Soluble in DMSO, ethanol (25 mg/ml), methanol, and dilute aqueous base.
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