Lappaconitine is an alkaloid isolated from the root of Aconltitum sinomantanum Nakai. Has a strong analgesic activity that does not involve the opioid receptor. It was shown to have class-I antiarrhythmic action and irreversibly blocks cloned human heart (hH1) channels by binding to the site 2 receptor.
Ono, M, Satoh T. Res Comm. Chem Path Pharm. 63:13-25 (1989). Heubach JF, Schule A. Planta Medica 64:22-26 (1998). Wright SN. Mol Pharm. 59:183-192 (2001).
Soluble in benzene, alcohol (Slightly), and ether (Slightly). Insoluble in water.
Store at 4° C
~720.7° C at 760 mmHg (Predicted)
~1.4 g/cm3 (Predicted)
n20D 1.62 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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