Labetalol hydrochloride CAS: 32780-64-6
MF: C19H24N2O3•HCl
MW: 364.87
A competitive a-adrenoceptor and b-adrenoceptor antagonist with antihypertensive properties.

Labetalol hydrochloride (CAS 32780-64-6)

Labetalol hydrochloride | CAS 32780-64-6 is rated 5.0 out of 5 by 1.
  • y_2021, m_7, d_30, h_19
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.18
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_252942, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 124ms
  • REVIEWS, PRODUCT
loading
5
1
4
0
3
0
2
0
1
0
Alternate Names: Amipress; Presdate; 2-Hydroxy-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]benzamide hydrochloride
Application: Labetalol hydrochloride is a competitive α-AR (α-adrenoceptor) and β-AR (β-adrenoceptor) antagonist with antihypertensive propertie
CAS Number: 32780-64-6
Molecular Weight: 364.87
Molecular Formula: C19H24N2O3•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
loading

a competitive a-adrenoceptor and b-adrenoceptor antagonist with antihypertensive properties.


References

Riva, E., et al., The å- and β-adrenoceptor blocking activities of labetalol and its RR-SR (50:50) stereoisomers. Br. J. Pharmacol. 104, 823-828, (1991) Fagan, S.C., et al., Acute hypertension promotes hemorrhagic transformation in a rabbit embolic stroke model: effect of labetalol. Exp. Neurol. 150, 153, (1998) Jaboureck-Bouttier, R., et al., Effects of two antihypertensive agents, labetalol and metoprolol, on the production of reactive oxygen species by normal polymorphonuclear leukocytes in vitro. Hypertens. Pregnancy 18, 239-247, (1999)

Appearance :
Powder
Physical State :
Solid
Solubility :
H2O: soluble: ethanol: soluble
Storage :
Store at 4° C
Melting Point :
178-180° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
SMILES :
CC(CCC1=CC=CC=C1)NCC(C2=CC(=C(C=C2)O)C(=O)N)O.Cl

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 109ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 5 out of 5 by from Xu Xu, et al. (PubMed ID 24572430) found that labetalol increased trophoblast integration into TNF-alpha pre-incubated endothelial networks. -SCBT Publication Review
Date published: 2015-06-23
  • y_2021, m_7, d_30, h_19
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.18
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_252942, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 14ms
  • REVIEWS, PRODUCT