L-Homoarginine (CAS 156-86-5)
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L-Homoarginine is a naturally occurring amino acid analog that has garnered attention in various research fields due to its structural similarity to L-arginine. In studies of biochemistry and physiology, L-Homoarginine is investigated for its role in the production of nitric oxide, a critical signaling molecule in the cardiovascular system. The compound is also of interest in the study of polyamine metabolism, where it may serve as a substrate or inhibitor of enzymes such as arginase and nitric oxide synthase. Moreover, L-Homoarginine is used in the synthesis of peptides and proteins that require modified amino acids to understand the structure-function relationship of these macromolecules. Research on L-Homoarginine also encompasses its influence on cellular signaling pathways and its potential to modulate biological processes through its interactions with various enzymes and transporters.
L-Homoarginine (CAS 156-86-5) References
- L-Homoarginine and L-arginine are antagonistically related to blood pressure in an elderly population: the Hoorn study. | van der Zwan, LP., et al. 2013. J Hypertens. 31: 1114-23. PMID: 23552121
- Possible sources and functions of L-homoarginine in the brain: review of the literature and own findings. | Bernstein, HG., et al. 2015. Amino Acids. 47: 1729-40. PMID: 25792110
- Influence of L-homoarginine as an analogue of L-arginine on the heat-induced aggregation of proteins. | Cirkovas, A. and Sereikaite, J. 2015. Biotechnol Prog. 31: 808-14. PMID: 25832546
- The prognostic biomarker L-homoarginine is a substrate of the cationic amino acid transporters CAT1, CAT2A and CAT2B. | Chafai, A., et al. 2017. Sci Rep. 7: 4767. PMID: 28684763
- L-Homoarginine and its AGXT2-metabolite GOCA in chronic kidney disease as markers for clinical status and prognosis. | Martens-Lobenhoffer, J., et al. 2018. Amino Acids. 50: 1347-1356. PMID: 29982953
- l-Homoarginine supplementation prevents diabetic kidney damage. | Wetzel, MD., et al. 2019. Physiol Rep. 7: e14235. PMID: 31552707
- Asymmetric dimethylarginine and L-homoarginine prospectively relate to carotid wall thickness in a South African cohort. | Mokhaneli, MC., et al. 2020. Amino Acids. 52: 965-973. PMID: 32613307
- Transport of L-Arginine Related Cardiovascular Risk Markers. | Banjarnahor, S., et al. 2020. J Clin Med. 9: PMID: 33302555
- L-homoarginine is associated with decreased cardiovascular- and all-cause mortality. | Mokhaneli, MC., et al. 2021. Eur J Clin Invest. 51: e13472. PMID: 33320332
- Lysine and homoarginine are closely interrelated metabolites in the rat. | Baskal, S., et al. 2022. Amino Acids. 54: 967-976. PMID: 35352207
- Pilot Study on Acute Effects of Pharmacological Intraperitoneal L-Homoarginine on Homeostasis of Lysine and Other Amino Acids in a Rat Model of Isoprenaline-Induced Takotsubo Cardiomyopathy. | Tsikas, D. and Redfors, B. 2022. Int J Mol Sci. 23: PMID: 35563125
- Evaluation of the predictive values of elevated serum L-homoarginine and dimethylarginines in preeclampsia. | Yuan, X., et al. 2022. Amino Acids. 54: 1215-1227. PMID: 35752997
- Comparative evaluation of the effect of L-Arginine and L-Homoarginine supplementation on reproductive physiology in ewes. | Chetla, VS., et al. 2022. Res Vet Sci. 149: 159-171. PMID: 35841692
- L-homoarginine studies provide insight into the antimetabolic properties of L-canavanine. | Rosenthal, GA. and Harper, L. 1996. Insect Biochem Mol Biol. 26: 389-94. PMID: 8814786
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L-Homoarginine, 5 g | sc-479071 | 5 g | $162.00 | |||
L-Homoarginine, 25 g | sc-479071A | 25 g | $427.00 |