KijanimicinAn antibacterial tetronic acid compound

Kijanimicin (CAS 78798-08-0)

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Application: An antibacterial tetronic acid compound
CAS Number: 78798-08-0
Purity: >99%
Molecular Weight: 1317.5
Molecular Formula: C67H100NO24
* Refer to Certificate of Analysis for lot specific data (including water content).
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Kijanimicin is a tetronic acid related to saccharocarcin, chlorothricin, versipelostatin and tetrocarcin. Like the tetrocarcins, kijanimicin contains an unusual nitro-aminoglycoside. Kijanimicin has potent antibacterial, antimalarial and antitumor activity.


References

1.Waitz, J.A., et al. 1981. J. Antibiot. 34: 1101-1106. PMID: 7328052
2. Bradner, W.T., et al. 1983. J. Antibiot. 36: 1078-1079. PMID: 6630059
3. Park, H.R., et al. 2004. J. Natl. Cancer Inst. 96: 1300-1310. PMID: 15339968
4. Nakajima, H., et al. 2007. Biochem. Biophys. Res. Commun. 356: 260-265. PMID: 17350598

Physical State :
Solid
Derived From :
Actinomadura sp.
Solubility :
Soluble in ethanol, methanol, DMF, DMSO, and water (limit).
Storage :
Store at -20° C
Density :
1.35 g/cm3 (Predicted)
Refractive Index :
n20D 1.60 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
5477557
MDL Number :
MFCD01939675
Beilstein Registry :
4948103
SMILES :
CC1CC(C(C2C1C3(C(C=C2)C(=CCC(C(=CC4C=C(C(CC45C(=O)C(=C(O5)O)C3=O)C)CO)C)OC6CC(C(C(O6)C)NC(=O)OC)(C)[N+](=O)[O-])C)C)OC7CC(C(C(O7)C)O)OC8CC(C(C(O8)C)OC9CC(C(C(O9)C)OC)O)OC1CC(C(C(O1)C)O)O)C

Download SDS (MSDS)

Certificate of Analysis

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