Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Protein transport across the nucleus is a selective, multi-step process involving several cytoplasmic factors that mediate protein passage through the nuclear pore complex (NPC). Cytoplasmic proteins that contain nuclear localization signals (NLSs) must be recognized as import substrates, dock at the nuclear pore complex and translocate across the nuclear envelope in an ATP-dependent fashion. Karyopherin α3, also known as KPNA3 or QIP2, is a 521 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one IBB domain and 10 ARM repeats. Expressed ubiquitously with highest expression in heart and skeletal muscle, karyopherin α3 binds to NLS-containing proteins, as well as to HIV-1 proteins, and directs their import into the nucleus. Additionally, karyopherin α3 functions as an adaptor protein for karyopherin β1 and helps regulate karyopherin β1-mediated docking of target substrates to the NPC complex. The gene encoding karyopherin α3 maps to human chromosome 13 and may be involved in the pathogenesis of schizophrenia.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Are there any issues with using sc-514101: karyopherin å3 (B-1) mouse monoclonal primary antibody on mouse samples?
Asked by: Trav11
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent,we recommend using a directly conjugated primary antibody. Please contact our special orders department for pricing and availability of sc-514101 conjugates.
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn
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