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Kanamycin Sulfate Solution (CAS 25389-94-0)

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Application:
Kanamycin Sulfate Solution is an inhibitor of protein synthesis in susceptible bacteria
CAS Number:
25389-94-0
Molecular Weight:
582.577
Molecular Formula:
C18H36N4O11•H2SO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Kanamycin Sulfate Solution is an aminoglycoside antibiotic consisting of a six-membered aminocyclitol ring attached to aminosugar side chains through glycosidic bonds. Kanamycin Sulfate Solution acts by inhibiting protein synthesis, and compromising translational fidelity in susceptible bacteria. It is active against most strains of gram-negative bacteria, many strains of gram-positive bacteria, and some strains of Mycobacterium. It is often used as a transgenic marker in plants and is most active in alkaline solution.


Kanamycin Sulfate Solution (CAS 25389-94-0) References

  1. Expression in transgenic tobacco of the bacterial neomycin phosphotransferase gene modified by intron insertions of various sizes.  |  Paszkowski, J., et al. 1992. Plant Mol Biol. 19: 825-36. PMID: 1322741
  2. Studies on the mechanism of action of kanamycin.  |  GOUREVITCH, A., et al. Antibiot Annu. 6: 784-9. PMID: 13637836
  3. Effect of neomycin and kanamycin on bacterial surface sites adsorbing C060 and vitamin B12.  |  DAVIS, RL., et al. Antibiot Annu. 7: 330-6. PMID: 13814515
  4. Drug-resistance test for kanamycin and cross resistance problem in Mycobacterium tuberculosis with special reference to kanamycin, streptomycin, and viomycin.  |  TSUKAMURA, M. 1959. J Antibiot (Tokyo). 12: 189-91. PMID: 13855139
  5. Examination of aqueous oxidized cellulose dispersions as a potential drug carrier. I. Preparation and characterization of oxidized cellulose-phenylpropanolamine complexes.  |  Zhu, L., et al. 2004. AAPS PharmSciTech. 5: e69. PMID: 15760066
  6. Generation of adult human induced pluripotent stem cells using nonviral minicircle DNA vectors.  |  Narsinh, KH., et al. 2011. Nat Protoc. 6: 78-88. PMID: 21212777
  7. Hexose Oxidase-Mediated Hydrogen Peroxide as a Mechanism for the Antibacterial Activity in the Red Seaweed Ptilophora subcostata.  |  Ogasawara, K., et al. 2016. PLoS One. 11: e0149084. PMID: 26867214
  8. Acidic Versus Alkaline Bacterial Degradation of Lignin Through Engineered Strain E. coli BL21(Lacc): Exploring the Differences in Chemical Structure, Morphology, and Degradation Products.  |  Morales, GM., et al. 2020. Front Bioeng Biotechnol. 8: 671. PMID: 32714907
  9. Changes in cardiovascular parameters in rats exposed to chronic widespread mechanical allodynia induced by hind limb cast immobilization.  |  Yoshimoto, T., et al. 2021. PLoS One. 16: e0245544. PMID: 33465131
  10. Low-Dose-Rate Irradiation Suppresses the Expression of Cell Cycle-Related Genes, Resulting in Modification of Sensitivity to Anti-Cancer Drugs.  |  Shimabukuro, K., et al. 2022. Cells. 11: PMID: 35159310
  11. Apo-metallothionein-3 cooperatively forms tightly compact structures under physiological conditions.  |  Yuan, AT., et al. 2023. J Biol Chem. 299: 102899. PMID: 36639030
  12. Utilization of carbon and nitrogen sources by Streptomyces kanamyceticus for kanamycin production.  |  Basak, K. and Majumdar, SK. 1973. Antimicrob Agents Chemother. 4: 6-10. PMID: 4791483
  13. Intracellular potassium. A determinant of the sodium-potassium pump rate.  |  Knight, AB. and Welt, LG. 1974. J Gen Physiol. 63: 351-73. PMID: 4817354

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Kanamycin Sulfate Solution, 6 x 50 ml

sc-29069
6 x 50 ml
$194.00