Juvenile hormone III CAS: 24198-95-6
MF: C16H26O3
MW: 266.38

Juvenile hormone III (CAS 24198-95-6)

Juvenile hormone III | CAS 24198-95-6 is rated 5.0 out of 5 by 1.
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Alternate Names: Juvenile hormone III is also known as trans-trans-10,11-Epoxyfarnesenic Acid methyl ester.
Application: Juvenile hormone III is a larval metamorphosis hormone, able to regulate processes such as adult larvae transition.
CAS Number: 24198-95-6
Purity: ≥65% (HPLC)
Molecular Weight: 266.38
Molecular Formula: C16H26O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Juvenile hormone III is a larval metamorphosis hormone, able to regulate processes such as adult larvae transition. Classified as an acyclic sesquiterpenoid, Juvenile hormone III also regulates oogenesis in adult female insects. Juvenile hormone III controls the larval metamorphosis of insects, including the retention of juvenile characteristics. During synthesis, Juvenile hormone III can be yielded from farnesoic by two alternative pathways. Juvenile hormone III activates the juvenile hormone receptor, known as methoprene-tolerant, with a Kd value of 2.9 nM.


References

1. Tillman, J.A., Seybold, S.J., Jurenka, R.A., et al.Insect pheromones--an overview of biosynthesis and endocrine regulation. Insect Biochemistry and Molecular Biology 29(6), 481-514 (1999).
2. Charles, J.P., Iwema, T., Epa, V.C., et al.Ligand-binding properties of a juvenile hormone receptor, methoprene-tolerant. Proceedings of the National Academy of Sciences of the United States of America 108(52), 21128-21133 (2011).
3. Defelipe, L.A., Dolghih, E., Roitberg, A.E., et al.Juvenile hormone synthesis: "Esterify then epoxidize" or "epoxidize then esterify"? Insights from the structural characterization of juvenile hormone acid methyltransferase. Insect Biochemistry and Molecular Biology 41(4), 228-235 (2011).
4. Navare, A.T., Mayoral, J.G., Nouzova, M., et al.Rapid direct analysis in real time (DART) mass spectrometric detection of juvenile hormone III and its terpene precursors. Analytical and Bioanalytical Chemistry 398(7-8), 3005-3013 (2010).

Physical State :
Liquid
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
MDL Number :
MFCD00135990
EC Number :
246-072-9
SMILES :
C/C(=C\\CC/C(=C/C(=O)OC)/C)/CC[[email protected]@H]1C(O1)(C)C

Download SDS (MSDS)

Certificate of Analysis

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Juvenile hormone III (CAS 24198-95-6)  Product Citations

See how others have used Juvenile hormone III (CAS 24198-95-6). Click on the entry to view the PubMed entry .

Citations 1 to 2 of 2 total

PMID: # 26216039  Reiff, T.|Jacobson, J.|Cognigni, P.|Antonello, Z.|Ballesta, E.|Tan, KJ.|Yew, JY.|Dominguez, M.|Miguel-Aliaga, I.| et al. 2015. Elife. 4: e06930.

PMID: # 23870282  Sen, R.|Raychoudhury, R.|Cai, Y.|Sun, Y.|Lietze, VU.|Boucias, DG.|Scharf, ME.| et al. 2013. BMC Genomics. 14: 491.

Citations 1 to 2 of 2 total

Juvenile hormonⅢをカブトムシの幼虫に施用する際は、どの程度に希釈するとよいですか?また、施用方法は、塗るべきでしょうか?それとも餌とともに摂食させるべきでしょうか? 教えてください。 参考文献等ありましたらお教えください。 

Asked by: 神田宮壱
Thank you for your question. Please contact our Technical Service Department and we will be happy to assist you. You may call us directly at 001 800-1338-3838, email at [email protected], or contact us by live chat. お問い合わせを頂きまして、誠にありがとうございました。お手数ですが、電話 001 800-1338-3838、メール[email protected]またはライブチャットで、当社のテクニカルサービスまでお問い合わせください。その他の不明点等がございましたら、またご連絡ください。
Answered by: Technical Support 8
Date published: 2018-12-21

May i please have any information on the solvent used or melt temp of the product as well as the density/ volume for the 10 mg quantity?

Asked by: 13punMA
Thank you for asking about our product Juvenile hormone III (CAS# 24198-95-6) We use Ethylacetate as a solvent in the final purification stage. It is low melting viscous liquid. 1 ml of JH III (Purity more than 65%)- weight is 0.997gm The density = Weight/ Volume = 0.997. Based on this 10mg (9.97mg) will be ~10µl
Answered by: Chemical Support 8
Date published: 2017-09-15

御社で販売されているJuvenile hormone IIIの純度はどのくらいでしょうか。 また、ロットを指定して購入することは可能でしょうか。 ご教示いただけると幸いです。 どうぞよろしくお願いいたします。

Asked by: nori54
お問い合わせを頂きまして、誠にありがとうございました。Juvenile hormone IIIの純度は≥65% (HPLC)です。ご注文の際、ロットを指定することができます。その他の不明点等がございましたら、またご連絡ください。どうぞよろしくお願いいたします。 Thank you for your question. The purity for sc-252931 is ≥65% (HPLC). If you would like to order a specific LOT#, please provide the LOT# when placing your order. Please feel free to contact me if I may be of further assistance.
Answered by: Technical Support 8
Date published: 2016-12-14
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Rated 5 out of 5 by from Clifton Clifton, ME. et al. (PubMed 24657670) found that male mosquitoes are able to alter the female's resource allocation priorities towards reproduction by transferring Juvenile Hormone III, which controls the larval metamorphosis of insects, including the retention of juvenile characteristics, during copulation. -SCBT Publication Review
Date published: 2015-01-07
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