JS-2190A P-glycoprotein and Mdr-1 inhibitor

JS-2190

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Synonym: Boc-Glu(OBzl)-N,N’-dicyclohexylurea
Application: A P-glycoprotein and Mdr-1 inhibitor
Purity: ≥98%
Molecular Weight: 543.69
Molecular Formula: C30H45N3O6
* Refer to Certificate of Analysis for lot specific data (including water content).
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JS-2190 is a Mdr-1(P-glycoprotein(Pgp)) and MRP1 inhibitor. Results obtained with the calcein assay protocol indicate that JS-2190 is efficiently taken up by living cells.


References

1. Hollo, Z., et al. 1994. Biochim. Biophys. Acta 1191: 384-388. PMID: 790969

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in chloroform (>10%), 100% ethanol, and ethanol: water 8:1 ( (mild heating up to 40° C).
Storage :
Store at -20° C
Density :
~1.16 g/cm3
Refractive Index :
n20D ~1.55 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
57347585
SMILES :
C1=CC=CC=C1COC(CCC(C(N(C(NC2CCCCC2)=O)C3CCCCC3)=O)NC(=O)OC(C)(C)C)=O

Download SDS (MSDS)

Certificate of Analysis

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