Anti-JNK1 Antibody (F-3) is a mouse monoclonal IgG1 κ JNK1 antibody, cited in 189 publications, provided at 200 µg/ml
raised against amino acids 1-384 representing full length JNK1 p46 p46 of human origin
Anti-JNK1 Antibody (F-3) is recommended for detection of all JNK1 p46 and p54 isoforms of mouse, rat and human origin by WB, IP, IF and IHC(P)
JNK1 Antibody (F-3) is available conjugated to agarose for IP; and to FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to either TRITC or Alexa Fluor® 405 for IF, IHC(P) and FCM
See JNK (D-2): sc-7345 for JNK1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of JNK1 (F-3): sc-1648.
m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for JNK1 Antibody (F-3) for WB and IHC(P) applications. These reagents are now offered in bundles with JNK1 Antibody (F-3) (see ordering information below).
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Labware ships FedEx Ground free of charge to the contiguous US
JNK1 Antibody (F-3) is a high quality monoclonal JNK1 antibody (also designated MAPK8 antibody or SAPK1 antibody) suitable for the detection of the JNK1 protein of mouse, rat and human origin. JNK1 Antibody (F-3) is available as both the non-conjugated anti-JNK1 antibody form, as well as multiple conjugated forms of anti-JNK1 antibody, including agarose, FITC and multiple Alexa Fluor® conjugates. c-Jun N-terminal kinases (JNKs) phosphorylate and augment transcriptional activity of c-Jun. JNKs originate from three genes that yield 10 isoforms through alternative mRNA splicing, including JNK1a1,JNK1b1, JNK2a1, JNK2b1, and JNK3a1, which represent the p46 isoforms, and JNK1a2, JNK1b2, JNK2a2, JNK2b2, and JNK3b2, which represent the p54 isoforms.JNKs coordinate cell responses to stress and influence regulation of cell growth and transformation. The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83% amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. Capsaicin activates JNK1 and p38 in ras-transformed human breast epithelial cells. Nitrogen oxides (NOx) upregulate JNK1 in addition to c-Fos, c-Jun, and other signaling kinases, including MEKK1 and p38.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences