isoquinoline-1,3(2H,4H)-dioneA useful isoquinoline for proteomics research

isoquinoline-1,3(2H,4H)-dione (CAS 4456-77-3)

isoquinoline-1,3(2H,4H)-dione | CAS 4456-77-3 is rated 5.0 out of 5 by 1.
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Application: A useful isoquinoline for proteomics research
CAS Number: 4456-77-3
Purity: ≥98%
Molecular Weight: 161.16
Molecular Formula: C9H7NO2
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits
Appearance :
Crystalline powder
Physical State :
Solid
Solubility :
Soluble in DMSO, and chloroform (3%).
Storage :
Store at room temperature
Melting Point :
234-236° C
Boiling Point :
377.15° C at 760 mmHg (Predicted)
Density :
1.29 g/cm3 (Predicted)
Refractive Index :
n20D 1.59 (Predicted)
IC50 :
Mitogen-activated protein kinase kinase kinase 14: IC50 = 51 µM (human)
pK Values :
pKa: 10.25 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
349435
MDL Number :
MFCD00234966
SMILES :
C1C2=CC=CC=C2C(=O)NC1=O

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Certificate of Analysis

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isoquinoline-1,3(2H,4H)-dione  Product Citations

See how others have used isoquinoline-1,3(2H,4H)-dione. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 26364592  Haljasorg, U. et al. 2015. European journal of immunology. 45: 3246-56.

Citations 1 to 1 of 1 total

What should I resuspend the compound in? and at what concentration? Also how should I store it after resuspension? I am looking for a product sheet but couldn't find one on your website.

Asked by: nmeednu
Thank you for your question. isoquinoline-1,3(2H,4H)-dione: sc-279244 is soluble in DMF and DMSO. The solubility in DMF is around 3% after ultrasound agitation. We cannot provide a solubility concentration for DMSO. It is recommended to use solutions the same day they are made. If you need to store the solution it is recommended to aliquot into useable amounts and freeze. Multiply freeze and thaw cycles should be avoided. We cannot provide a shelf-life. You can request a Safety Datasheet (SDS), or a lot-specific Certificate of Analysis (CoA) on our website. Those are the only product sheet(s) available for this product.
Answered by: Technical Support
Date published: 2017-02-08

What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. This chemical is supplied as an off-white crystalline powder. Please contact Technical Service if you have further questions concerning this product.
Answered by: Tech Service 9
Date published: 2017-01-18
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Rated 5 out of 5 by from Various publications cite the use of isoquinoline Various publications cite the use of isoquinoline-1,3(2H,4H)-dione for proteomics research. -SCBT Publication Review
Date published: 2015-07-13
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