Isoflurane CAS: 26675-46-7
MF: C3H2ClF5O
MW: 184.49

Isoflurane (CAS 26675-46-7)

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Alternate Names: Isoflurane is also known as (±)-Isoflurane.
Application: Isoflurane is a halogenated ether with anesthetic properties, useful solvent for dispersing fluorinated materials.
CAS Number: 26675-46-7
Purity: ≥97%
Molecular Weight: 184.49
Molecular Formula: C3H2ClF5O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Isoflurane is a halogenated ether. The anesthtetic properties of Isoflurane make it a desirable component in anesthetic formulations. Although its mechanism is still being understood, Isoflurane anesthesia has shown promising results in mice. Research suggests a relationship between postoperative cognitive dysfunction and isoflurane inhalation anesthesia.


References

1. Wang, X., Song, Z.G., Huang, D.X., et al.A single nucleotide polymorphism in GABAA receptor isoforms is potentially responsible for isoflurane sensitivity in mice. Genet. Mol. Res. 15(2), gmr.15027340 (2016).
2. Jiang, S., Miao, B., and Chen, Y.Prolonged duration of isoflurane anesthesia impairs spatial recognition memory through the activation of JNK1/2 in the hippocampus of mice. Neuroreport. 28(7), 386-390 (2017).
3. Lewis, M.C. et al.: Med. Hypoth., 68, 484 (2007)
4. Mellon, R.D. et al.: Anesth. Analg., 104, 509 (2007)
5. Xie et al (2007) The inhalation anesthetic isofl. induces a vicious cycle of apoptosis and amyloid β-protein accumulation. J.Neuroscience 27 1247

Physical State :
Liquid
Solubility :
Soluble in water (4.47 mg/ml at 37° C), and organic liquids including fats and oils.
Storage :
Store at 4° C
Melting Point :
48-48.5° C
Boiling Point :
48-49° C
Density :
1.50 g/mL at 20° C
Refractive Index :
n20D 1.30
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
KN6799000
PubChem CID :
Merck Index :
14: 5175
MDL Number :
MFCD00066609
EC Number :
247-897-7
Beilstein Registry :
1852087
SMILES :
C(C(F)(F)F)(OC(F)F)Cl

Download SDS (MSDS)

Certificate of Analysis

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Isoflurane (CAS 26675-46-7)  Product Citations

See how others have used Isoflurane (CAS 26675-46-7). Click on the entry to view the PubMed entry .

Citations 1 to 6 of 6 total

PMID: # 28666687  Surgery. 863-870.

PMID: # 31807042  Diabetes Metab Syndr Obes. 12: 2289-2302.

PMID: # 28901439  Mol Med Rep. 16: 7039-7047.

PMID: # 32012798  Int J Mol Sci. 21:

PMID: # 32813905  Eur J Neurosci.

PMID: # 33167919  BMC Cancer. 1076.

Citations 1 to 6 of 6 total

Hi, Does the Isoflurane come in a liquid or a powder? I would prefer not to have to make it up in solution. Thank you.

Asked by: aek19805
Thank you for your question. Isoflurane (CAS 26675-46-7) is provided in a liquid state. This information is provided on our website in the Technical Information, below the Ordering Information on the product page.
Answered by: Technical Support
Date published: 2020-10-28
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