IQGAP1 CRISPR Plasmids (m) mouse IQGAP1-specific CRISPR/Cas9 KO Plasmid, HDR Plasmid, Double Nickase Plasmids, CRISPR Activation Plasmids and Lentiviral Activation Particles

IQGAP1 CRISPR Plasmids (m)

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    • Target species: mouse; for corresponding human product, see IQGAP1 CRISPR Plasmids (h)
    • CRISPR/Cas9 KO Plasmids consists of IQGAP1-specific 20 nt guide RNA sequences derived from the GeCKO (v2) library
    • For CRISPR gene knockout, gRNA sequences direct the Cas9 protein to induce a site-specific double strand break (DSB) in the genomic DNA
    • Target-specific CRISPR Plasmids for both gene knockout and activation are available. Please refer to the detailed product information in the tabs below
    • Gene knockdown or activation can be assayed using IQGAP1 Antibody (C-9): sc-376021
    • All products are provided as transfection-ready, purified plasmid DNA, except the Lentiviral Activation Particles which have been prepackaged as Lentiviral Particles for use with hard-to-transfect cells

Gene Info

SpeciesGene NameGene IDChromosome LocationIsoform (mRNA) Accession #Protein Accession #OMIM™ Number
MouseIqgap1298757 D3XM_006540950, NM_016721Q9JKF1N/A

Hi, before we buy this product, we were wondering where in the mouse IQGAP1 gene do the three sgRNA target for the Cas9 nuclease. Furthermore, I would like to know whether the presence of IQGAP2 and IQGAP3 would interfere with the IQGAP1 KO experiment?

Asked by: Anish
Thank you for your question. Please contact our Technical Service Department and we can provide you with the targeted exon information for the specific guide RNA in this product. After you purchase the product, we can provide the specific gRNA sequences upon request. Regarding your latter question, this is a research question and we would not be able to accurately answer it without conducting such experiments of our own.
Answered by: Technical Support
Date published: 2019-01-26
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