Interleukin-1 Receptor-Associated-Kinase-1/4 InhibitorA potent and selective inhibitor of IL-1 kinases

Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor (CAS 509093-47-4)

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Synonym: 1-(2-(4-Morpholinyl)ethyl)-2-(3-nitrobenzoylamino)benzimidazole; N-(2-Morpholinylethyl)-2-(3-nitrobenzoylamido)-benzimidazole
Application: A potent and selective inhibitor of IL-1 kinases
CAS Number: 509093-47-4
Purity: ≥95%
Molecular Weight: 395.42
Molecular Formula: C20H21N5O4
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Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor is a benzimidazole compound that acts as a cell-permeable, potent selective inhibitor of IL-1 kinases. Shown to exhibit little activity against a panel of 27 other kinases, including, but not limited to, Ick and src.


Bhattacharyya, S., et al. 2007. Am. J. Physiol. Gastrointest. Liver Physiol. 293, G429. Powers, J.P., et al. 2006. Bioorg. Med. Chem. Lett. 16, 2842.

Appearance :
Physical State :
Solubility :
Soluble in DMSO
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :

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Asked by: FariasAB
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Answered by: Technical Support
Date published: 2017-09-20
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