Indole-3-carboxaldehyde (CAS 487-89-8)
QUICK LINKS
Indole-3-carboxaldehyde is a chemical compound that functions as a key intermediate in the synthesis of various organic compounds. It acts as a precursor in the production of indole-3-carboxylic acid, which is an important building block for the synthesis of phytohormones and other biologically active molecules. At the molecular level, it undergoes various chemical reactions to form complex organic structures, contributing to the development of diverse compounds with potential biological activity. Its mechanism of action involves participating in condensation reactions and other chemical transformations, leading to the formation of structurally diverse molecules with potential applications in development. In experimental applications, it serves as a versatile starting material for the synthesis of novel compounds, contributing to the exploration of new chemical entities and their potential biological activities.
Indole-3-carboxaldehyde (CAS 487-89-8) References
- Electrochemical behavior of indole-3-carboxaldehyde izonicotinoyl hydrazones: discussion on possible biological behavior. | Shirinzadeha, H., et al. 2010. Comb Chem High Throughput Screen. 13: 619-27. PMID: 20426736
- Seborrheic dermatitis: etiology, risk factors, and treatments: facts and controversies. | Dessinioti, C. and Katsambas, A. 2013. Clin Dermatol. 31: 343-351. PMID: 23806151
- The Biosynthetic Pathway of Indole-3-Carbaldehyde and Indole-3-Carboxylic Acid Derivatives in Arabidopsis. | Böttcher, C., et al. 2014. Plant Physiol. 165: 841-853. PMID: 24728709
- Plant-Derived Exosomal MicroRNAs Shape the Gut Microbiota. | Teng, Y., et al. 2018. Cell Host Microbe. 24: 637-652.e8. PMID: 30449315
- Indole-3-carboxaldehyde regulates RSV-induced inflammatory response in RAW264.7 cells by moderate inhibition of the TLR7 signaling pathway. | Hou, X., et al. 2021. J Nat Med. 75: 602-611. PMID: 33755912
- Enteric formulated indole-3-carboxaldehyde targets the aryl hydrocarbon receptor for protection in a murine model of metabolic syndrome. | Puccetti, M., et al. 2021. Int J Pharm. 602: 120610. PMID: 33865951
- Indole-3-Carboxaldehyde Restores Gut Mucosal Integrity and Protects from Liver Fibrosis in Murine Sclerosing Cholangitis. | D'Onofrio, F., et al. 2021. Cells. 10: PMID: 34209524
- Development and in vitro-in vivo performances of an inhalable indole-3-carboxaldehyde dry powder to target pulmonary inflammation and infection. | Puccetti, M., et al. 2021. Int J Pharm. 607: 121004. PMID: 34391857
- Optimizing therapeutic outcomes of immune checkpoint blockade by a microbial tryptophan metabolite. | Renga, G., et al. 2022. J Immunother Cancer. 10: PMID: 35236743
- Effects of Dietary Indole-3-carboxaldehyde Supplementation on Growth Performance, Intestinal Epithelial Function, and Intestinal Microbial Composition in Weaned Piglets. | Zhang, R., et al. 2022. Front Nutr. 9: 896815. PMID: 35651506
- Ginsenoside Rg1 Alleviates Acute Ulcerative Colitis by Modulating Gut Microbiota and Microbial Tryptophan Metabolism. | Cheng, H., et al. 2022. Front Immunol. 13: 817600. PMID: 35655785
- Indole-3-Carboxylic Acid From the Endophytic Fungus Lasiodiplodia pseudotheobromae LPS-1 as a Synergist Enhancing the Antagonism of Jasmonic Acid Against Blumeria graminis on Wheat. | Que, Y., et al. 2022. Front Cell Infect Microbiol. 12: 898500. PMID: 35860382
- Indole-3-carboxaldehyde ameliorates ionizing radiation-induced hematopoietic injury by enhancing hematopoietic stem and progenitor cell quiescence. | Guan, D., et al. 2023. Mol Cell Biochem.. PMID: 37067732
- The Tryptophan Metabolite Indole-3-Carboxaldehyde Alleviates Mice with DSS-Induced Ulcerative Colitis by Balancing Amino Acid Metabolism, Inhibiting Intestinal Inflammation, and Improving Intestinal Barrier Function. | Liu, M., et al. 2023. Molecules. 28: PMID: 37175112
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Indole-3-carboxaldehyde, 5 g | sc-257609 | 5 g | $29.00 |