Indirubin-3prime-(2,3-dihydroxypropyl)shyoximether MF: C19H17N3O4
MW: 351.35
A c-Src inhibitor (IC50=0.43µM).

Indirubin-3′-(2,3-dihydroxypropyl)shyoximether

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Alternate Names: E804
Application: Indirubin-3′-(2,3-dihydroxypropyl)oximether is a c-Src inhibitor (IC50=0.43µM)
Molecular Weight: 351.35
Molecular Formula: C19H17N3O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Indirubin-3'-(2,3-dihydroxypropyl)oximether is a c-Src inhibitor (IC50=0.43µM) blocking downstream STAT3 signalling. Also, induces apoptosis in human cancer cells.


References

Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells: S. Nam, et al.; PNAS 102, 5998 (2005)

Physical State :
Solid
Solubility :
Soluble in DMSO (1M).
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
SMILES :
C1=CC=C2C(=C1)C(=C(N2)C3=C4C=CC=CC4=NC3=O)NOCC(CO)O

Download SDS (MSDS)

Certificate of Analysis

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Indirubin-3prime-(2,3-dihydroxypropyl)shyoximether  Product Citations

See how others have used Indirubin-3prime-(2,3-dihydroxypropyl)shyoximether. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 26386687  Zhang, Y.|Du, Z.|Zhuang, Z.|Wang, Y.|Wang, F.|Liu, S.|Wang, H.|Feng, H.|Li, H.|Wang, L.|Zhang, X.|Hao, A.| et al. 2015. J Neurooncol. 125: 265-75.

Citations 1 to 1 of 1 total
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