INCB 3284 dimesylateA selective and potent hCCR2 antagonist

INCB 3284 dimesylate (CAS 887401-93-6)

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Synonym: Dimesylate
Application: A selective and potent hCCR2 antagonist
CAS Number: 887401-93-6
Molecular Weight: 712.76
Molecular Formula: C26H31F3N4O4.2CH4O3S
* Refer to Certificate of Analysis for lot specific data (including water content).
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Physical State :
Solid
Solubility :
Soluble in water (100 mM), and DMSO (100 mM).
Storage :
Store at -20° C
IC50 :
Monocyte chemoattractant molecule binding to hCCR2: IC50 = 3.7 nM; Chemotaxis activity: IC50 = 4.7 nM; hERG potassium current: IC50 = 84 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
11679268
MDL Number :
MFCD20926352
SMILES :
COC1=NC=C(C=C1)C2(CCC(CC2)N3CC[C@H](C3)NC(=O)CNC(=O)C4=CC(=CC=C4)C(F)(F)F)O.CS(=O)(=O)O.CS(=O)(=O)O

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Certificate of Analysis

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