iMAC2 CAS: 335166-00-2
MF: C19H20Br2FN3•2HCl
MW: 542.11
A mitochondrial apoptosis-induced channel (MAC) inhibitor.

iMAC2 (CAS 335166-00-2)

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Alternate Names: 3,6-Dibromo-9-[2-fluoro-3-(1-piperazinyl)propyl]-9H-carbazole dihydrochloride
Application: iMAC2 is iMAC2 Iis a mitochondrial apoptosis-induced channel (MAC) inhibitor
CAS Number: 335166-00-2
Molecular Weight: 542.11
Molecular Formula: C19H20Br2FN32HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

iMAC2 inhibits mitochondrial apoptosis-induced channel (MAC) (IC50 = 28 nM). It has been shown to reduce STS-induced apoptosis in FL5.12 cells by over 50%. Inhibits release of cytochrome c by Bid-induced Bax activation (IC50 = 0.68 μM).

Physical State :
Solid
Solubility :
Soluble in DMSO (5 mM).
Storage :
Store at 4° C
IC50 :
MAC: IC50 = 28 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
SMILES :
C1CN(CCN1)CC(CN2C3=C(C=C(C=C3)Br)C4=C2C=CC(=C4)Br)F.Cl.Cl

Download SDS (MSDS)

Certificate of Analysis

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