Illudin SA potent antitumor sesquiterpene

Illudin S (CAS 1149-99-1)

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Synonym: Lampterol
Application: A potent antitumor sesquiterpene
CAS Number: 1149-99-1
Purity: ≥98%
Molecular Weight: 264.32
Molecular Formula: C15H20O4
* Refer to Certificate of Analysis for lot specific data (including water content).
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Illudin S is potent antitumor sesquiterpene, first isolated from the fungus, Clitocybe illudens, in 1963. Illudin S is metabolically activated to reactive intermediates that bind DNA. The DNA damage appears to differ from that of other reactive metabolites. Importantly, illudin S exhibits in vitro and in vivo potency against multi-drug resistant tumours.

Physical State :
Solid
Derived From :
Pleurotus lampas
Solubility :
Soluble in ethanol, methanol, DMSO, DMF, and water (limited).
Storage :
Store at -20° C
Melting Point :
171.93° C (Predicted)
Boiling Point :
~509.6° C at 760 mmHg (Predicted)
Density :
~1.3 g/cm3 (Predicted)
Refractive Index :
n20D 1.62 (Predicted)
IC50 :
HL-60: IC50 = 3 nM (human)
pK Values :
pKa: 12.5 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
WH0204300
PubChem CID :
344200
MDL Number :
MFCD00870487
SMILES :
CC1=C2[C@H]([C@](C=C2C(=O)[C@](C13CC3)(C)O)(C)CO)O

Download SDS (MSDS)

Certificate of Analysis

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