IL-11 Antibody (A-7) is a mouse monoclonal IgG2a (kappa light chain) provided at 200 µg/ml
raised against amino acids 31-199 of IL-11 of human origin
recommended for detection of IL-11 of human origin by WB, IP, IF and ELISA
m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for IL-11 Antibody (A-7) for WB applications. These reagents are now offered in bundles with IL-11 Antibody (A-7) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Interleukin-11, or IL-11, is a pleiotropic cytokine that is biologically related to IL-6, leukemia inhibitory factor (LIF), oncostatin M (OSM) and ciliary neurotrophic factor (CNTF). IL-11 is a stromal cell-derived cytokine which stimulates the proliferation of primitive hematopoietic progenitor cells and, together with Flt 3-L, stimulates the expansion of CD34+ cell populations. Human IL-11 cDNA encodes a 199 amino acid precursor with a 21 amino acid hydrophobic signal peptide which is cleaved to generate a glycosylated biologically active form. IL-11 exerts its biological effects through the interleukin-11 receptor, IL-11R, which is composed of an IL-11 receptor-specific chain designated IL-11Rα, and gp130, the signal transducing component common to the IL-6, LIF, OSM and CNTF receptors. Stimulation of the IL-11R results in the activation of the Janus tyrosine kinase family members JAK1 and JAK2 which, once activated, induce the nuclear translocation of the transcription factors Stat1 and Stat3.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.