IFT172 Antibody (A-11) is a mouse monoclonal IgG1 (kappa light chain) provided at 200 µg/ml
raised against amino acids 1353-1652 mapping within an internal region of IFT172 of human origin
IFT172 Antibody (A-11) is recommended for detection of IFT172 of mouse, rat and human origin by WB, IP, IF and ELISA
IFT172 Antibody (A-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of IFT172 (A-11): sc-398393.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Intraflagellar transport is mediated by a variety of intraflagellar transport proteins (IFTs) that work in tandem to mediate ciliary and flagellar process assembly. Endogenous IFT proteins are most highly expressed within the inner segment, around the basal body, and within the outer segment.Additionally, IFT proteins are localized in discrete particles along the entire length of the axoneme. IFT proteins are divided into two subcomplexes, A and B, which contain at least 6 or 11 subunits, respectively. IFT-A proteins are associated with retrograde transport, whereas IFT-B proteins are thought to be involved in structure because, in their absence, cilia and flagella may be truncated, or completely absent. IFT172 (intraflagellar transport 172), also known as SLB, wim or osm-1, is a 1,749 amino acid protein that belongs to the IFT172 family and localizes to the cilium. Containing fourteen TPR repeats and nine WD repeats, IFT172 is required for the maintenance and formation of cilia. IFT172 plays an indirect role in Shh signaling, with cilia being required for all activity of the hedgehog pathway.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences