ID 8

ID 8 (CAS 147591-46-6)

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Synonym: 1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol
Application: Sustains self-renewal and pluripotency of mouse ESCs
CAS Number: 147591-46-6
Molecular Weight: 298.29
Molecular Formula: C16H14N2O4
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).
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ID 8 has been shown to sustain self-renewal and pluripotency of mouse embryonic stem cells (ESCs) in vitro. Additional studies have shown that ID 8 stimulates proliferation at a steady rate.


References

1. Miyabayashi, Tomoyuki., et al., 2008. Indole derivatives sustain embryonic stem cell self-renewal in long-term culture. Bioscience, biotechnology, and biochemistry. 72(5): 1242-8. PMID: 18460821
2. Firestone, Ari J., et al., 2010. Controlling destiny through chemistry: small-molecule regulators of cell fate. ACS chemical biology. 5(1): 15-34. PMID: 20000447

Physical State :
Solid
Solubility :
DMSO (10 mM)
Storage :
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Transport :
UN 3077, Class 9, Packing group III
PubChem CID :
791637
SMILES :
CC1=C(C2=C(N1C3=CC=C(C=C3)OC)C=C(C=C2)O)[N+](=O)[O-]

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Certificate of Analysis

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