Ibandronate Sodium MonohydrateAn inhibitor of bone resorption

Ibandronate Sodium Monohydrate (CAS 138926-19-9)

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Application: An inhibitor of bone resorption
CAS Number: 138926-19-9
Purity: ≥99%
Molecular Weight: 359.23
Molecular Formula: C9H24NNaO8P2
* Refer to Certificate of Analysis for lot specific data (including water content).
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Ibandronate Sodium Monohydrate inhibits bone resorption as a sodium salt and complexed with technetium Tc 99m for bone imaging. The monophosphonates are not active and the biphosphonates are used in disorders affecting the skeleton such as metastatic disease, asteoporosis and Paget's. Ibandronate Sodium Monohydrate is an inhibitor of FDPS.


References

Muhlbauer, R.C., et al.: J. Bone Miner. Res., 6, 1003 (1991) Pecherstorfer, M., et al.: J. Clin. Oncol., 14, 268 (1996)

Physical State :
Solid
Solubility :
Soluble in water (72 mg/ml at 25° C), ethanol (<1 mg/ml at 25° C), and DMSO (<1 mg/ml at 25° C).
Storage :
Store at -20° C
Melting Point :
175-177° C
Boiling Point :
587.8° C at 760 mmHg (Predicted)
Refractive Index :
n20D 1.54 (Predicted)
IC50 :
FDPS: IC50 = 20 nM; Squalene synthetase: IC50 = 0.64 µM (rat); Trypanosoma brucei rhodesiense: IC50 = 0.96 µM; Entamoeba histolytica: IC50 = 54 µM; HFF: IC50 = 54.92 µM (human)
Ki Data :
FDPS: Ki= 3.6 nM (human)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
SZ8563300
PubChem CID :
23663991
MDL Number :
MFCD00912167
SMILES :
CCCCCN(C)CCC(O)(P(=O)(O)O)P(=O)(O)[O-].O.[Na+]

Download SDS (MSDS)

Certificate of Analysis

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What is the best price of 5 Kg lot Ibandronate Sodium Monohydrate: CAS # -218589... Ibandronate Sodium Monohydrate: sc-218589 Ibandronate Sodium Monohydrate (CAS 138926-19-9) CPT C10% ON DHAKA BY AIR. Kindly offer your best price.

Asked by: Muhammad Harunur Rashid
Thank you for your inquiry and your interest in this product. For requests regarding price quotations, availability or lead time please contact our Customer Service by phone, (800)-457-3801 option 1, email &lt;scbt@scbt.com&gt;, or by live chat directly on our website, www.scbt.com. We are happy to assist you.
Answered by: Technical Support Europe
Date published: 2017-12-27

What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. Ibandronate Sodium Monohydrate, sc-218589, is in white crystalline powder form.
Answered by: Chemical Support 4
Date published: 2017-06-30
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