Hydroxychloroquine SulfateAn antimalarial and antirheumatic

Hydroxychloroquine Sulfate (CAS 747-36-4)

Hydroxychloroquine Sulfate | CAS 747-36-4 is rated 5.0 out of 5 by 1.
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Synonym: 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol Sulfate; 7-Chloro-4-[4-[ethyl(2-hydroxyethyl)amino]-1-methylbutylamino]-quinoline Sulfate; Ercoquin; Plaquenil Sulfate; Quensyl
Application: An antimalarial and antirheumatic
CAS Number: 747-36-4
Purity: ≥97%
Molecular Weight: 433.95
Molecular Formula: C18H26ClN3O•H2SO4
* Refer to Certificate of Analysis for lot specific data (including water content).
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Hydroxychloroquine Sulfate is a lupus erythematosus suppressant as well as an antimalerial and antirheumatic.


References

Yarden, Y., et al.: Nature, 323, 226 (1986), Seifert, R., et al.: J. Biol. Chem., 264, 8771 (1989), Gahl, W., et al.: Mol. Genet. Metab., 76, 234 (2002), Card, J., et al.: Toxicol. Sci., 75, 169 (2003),

Physical State :
Solid
Solubility :
Soluble in water (> 20 mg/mL).
Storage :
Store at 4° C
Melting Point :
≥ 260° C (lit.)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
12947
MDL Number :
MFCD00078203
EC Number :
212-019-3
SMILES :
CCN(CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)CCO.OS(=O)(=O)O

Download SDS (MSDS)

Certificate of Analysis

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Hydroxychloroquine Sulfate  Product Citations

See how others have used Hydroxychloroquine Sulfate. Click on the entry to view the PubMed entry .

Citations 1 to 2 of 2 total

PMID: # 27070720  Patel, K. et al. 2016. Molecular pharmaceutics. 13: 2049-58.

PMID: # 25187658  Le, NT. et al. 2014. J. Immunol. 193: 3803-15.

Citations 1 to 2 of 2 total

What the max. solubility of this CQ compound? "Solubility : Soluble in Water"

Asked by: Arnaud
Thank you for your question. This chemical, Hydroxychloroquine Sulfate: sc-215157, is soluble in water at a concentration of > 20 mg/mL.
Answered by: Technical Support
Date published: 2018-07-22
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Rated 5 out of 5 by from Xu Xu, C. et al. (PubMed 26429523) reported that chloroquine and Hydroxychloroquine are novel inhibitors of human organic anion transporting polypeptide 1A2. -SCBT Publication Review
Date published: 2015-01-21
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