Anti-hnRNP A2/B1 Antibody (B-7) is a mouse monoclonal IgG2b κ hnRNP A2/B1 antibody, cited in 6 publications, provided at 200 µg/ml
specific for an epitope mapping between amino acids 209-243 within an internal region of hnRNP A2/B1 of human origin
Anti-hnRNP A2/B1 Antibody (B-7) is recommended for detection of hnRNP A2/B1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine and porcine
Anti-hnRNP A2/B1 Antibody (B-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of hnRNP A2/B1 (B-7): sc-374053.
m-IgG Fc BP-HRP and m-IgG2b BP-HRP are the preferred secondary detection reagents for hnRNP A2/B1 Antibody (B-7) for WB and IHC(P) applications. These reagents are now offered in bundles with hnRNP A2/B1 Antibody (B-7) (see ordering information below).
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Labware ships FedEx Ground free of charge to the contiguous US
hnRNP A2/B1 Antibody (B-7) is a high quality monoclonal hnRNP A2/B1 antibody (also designated HNRNPA2B1 antibody) suitable for the detection of the hnRNP A2/B1 protein of mouse, rat and human origin. hnRNP A2/B1 Antibody (B-7) is available as both the non-conjugated anti-hnRNP A2/B1 antibody form, as well as multiple conjugated forms of anti-hnRNP A2/B1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of poly-peptides that contribute to mRNA transcription and pre-mRNA processing as well as mature mRNA transport to the cytoplasm and translation. They also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA polymerase II. There are approximately 20 known hnRNP proteins, and their complexes are the major constituents of the spliceosome. The majority of hnRNP proteins are localized to the nucleus; however some shuttle between the nucleus and the cytoplasm. The A/B subfamily of hnRNPs include A1, A2/B1, A3 and A0, and in Xenopus, hnRNP A1, A2 and A3 are ubiquitously expressed throughout development as well as in adult tissues. hnRNP A1 and A2/B1 regulate the processing of pre-mRNA by directly antagonizing the association of various splicing factors and by influencing the splice site selection on pre-mRNA. The hnRNP A0 gene is distinct from the other A/B family members, and it encodes a low-abundance protein, which is implicated in mRNA stability.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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