Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
The major histocompatibility complex (MHC) is a high genomic density gene family that plays an important role in the immune system, autoimmunity and reproductive success. Human MHC genes are referred to as human leukocyte antigen (HLA) genes. MHC class I molecules consist of two polypeptide chains, an a or heavy chain, and β-2-Microglobulin, a non-covalently associated protein. Cytotoxic T lymphocytes bind antigenic peptides presented by MHC class I molecules. Antigens that bind to MHC class I molecules are typically 8-10 residues in length and are stabilized in a peptide binding groove. Accumulating in endosomal/lysosomal compartments and on the surface of B cells, HLA-DM and -DO molecules regulate binding of exogenous peptides to class II molecules (HLA-DR) by sustaining a conformation that favors peptide exchange. The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Rated 5 out of
Good antibodyThe HLA class I Antibody (YTH862.2): sc-59206 provides good data for Western blotting applications, showing clear banding with minimal background. This antibody has also been cited for further verification.
Date published: 2017-01-30
Rated 5 out of
Single strong band for WB in human PBL wholeSingle strong band for WB in human PBL whole cell lysate. -SCBT QC
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn
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