HLA-A2 Antibody (BB7.2) is a mouse monoclonal IgG2b (kappa light chain) provided at 200 µg/ml
raised against solubilized HLA-A2
HLA-A2 Antibody (BB7.2) is recommended for detection of epitope on α 2 domain of HLA-A2 of human origin by FCM
HLA-A2 Antibody (BB7.2) is available conjugated to either phycoerythrin or FITC for FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of HLA-A2 (BB7.2): sc-32236.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
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Please note: We can not ship to PO boxes
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Human leukocyte antigen A2 (HLA-A2) is a human class I histocompatibility (MHC I) molecule. MHC I molecules are integral parts of the immune response and present peptides on the cell surface to T lymphocytes (CTLs). HLA-A2 is associated with interferon-a therapy-induced autoimmune thyroid dysfunction in patients with chronic hepatitis C. In primary T cells, HIV evasion of the cellular immune response reveals that HLA-A2 antigens are downmodulated more dramatically than total MHC class I antigens. Downregulation of MHC class I HLA-A2 antigens occurs not only in primary T cells, but also in b and astrocytoma cell lines. Heavy chain modifications to HLA-A2 enhance the presentation of defined HIV-1 epitope-specific CTL target structures. Incorpo-ration of HIV-1 CTL epitopes into the signal sequence of HLA or tethering of epitopes to the HLA-A2 heavy chain provide simple ways to create effective CTL target structures which can be recognized and lysed by human HLA-A2 restricted RT-specific CD8+ CTL.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Does your antibody distinguish between specific subtypes of HLA-A2 such as HLA*02:01 and HLA*02:06?
Asked by: rmeaston
Thank you for your question. According to the following publication, this clone, BB7.2, has been shown to have polymorphic specificity. Please refer to the publication below for more detailed information.
Answered by: Technical Support
Date published: 2019-05-17
Is it suitable for western blot?
Asked by: vandana
Thank you for your question. No, this antibody is not recommended for Western blot.
Answered by: Technical Support
Date published: 2019-01-26
What negative control should be used when using the conjugated version of HLA-A2 (BB7.2): sc-32236 monoclonal antibody in flow cytometry?
Asked by: jenni
Thank you for your inquiry. We recommend using the isotype specific normal mouse IgG conjugated to the same fluorophore. For example, if you are using sc-32236 PE, then you would want to use normal mouse IgG2b PE, sc-2868.
Answered by: Technical Support 15
Date published: 2017-01-12
Which secondary antibody do you recommend using with HLA-A2 (BB7.2): sc-32236?
Asked by: jenni
Thank you for your question. While most anti-mouse IgG secondary antibodies are appropriate for use with HLA-A2 (BB7.2): sc-32236 monoclonal antibody we recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here:
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn
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