Histamine dihydrochlorideA potent vasodilator and endogenous histamine receptor agonist

Histamine dihydrochloride (CAS 56-92-8)

Histamine dihydrochloride | CAS 56-92-8 is rated 5.0 out of 5 by 1.
  • y_2019, m_11, d_15, h_20
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.2
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_202650, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 75ms
  • REVIEWS, PRODUCT
5
1
4
0
3
0
2
0
1
0
Synonym: 2-(4-Imidazolyl)ethylamine dihydrochloride
Application: A potent vasodilator and endogenous histamine receptor agonist
CAS Number: 56-92-8
Purity: ≥97%
Molecular Weight: 184.07
Molecular Formula: C5H9N32HCl
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Histamine dihydrochloride is a potent vasodilator that acts as an agonist for endogenous histamine receptors (H1-4). The activation of histamine receptors mobilizes Ca2+ and stimulates adenylate cyclase activity in neurons. This compound can stimulate gastric secretion, constrict bronchial smooth muscle, act as a neurotransmitter, and activate nitric oxide.


References

1. Fu, L.W., et al. 1997. Am. J. Physiol. 273: H2726-H2737. PMID: 9435609
2. Maintz, L. and Novak, N. 2007. Am. J. Clin. Nutr. 85: 1185-1196. PMID: 17490952
3. Thurmond, R.L., et al. 2008. Nat Rev Drug Discov. 7: 41-53. PMID: 18172439

Physical State :
Solid
Solubility :
Soluble in water (100 mg/ml), ether, methanol (freely), and DMSO (100 mM).
Storage :
Store at 4° C
Melting Point :
247-249° C
Density :
0.63 g/cm3 at 20° C (tautomer)
Refractive Index :
n20D ~1.57 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
2
RTECS :
MS1575000
PubChem CID :
5818
Merck Index :
14: 4719
MDL Number :
MFCD00012703
EC Number :
200-298-4
Beilstein Registry :
3624116
SMILES :
C1=C(NC=N1)CCN.Cl.Cl

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

Histamine dihydrochloride  Product Citations

See how others have used Histamine dihydrochloride. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 9435609  Fu, LW. et al. 1997. Am. J. Physiol. 273: H2726-H2737.

Citations 1 to 1 of 1 total
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 61ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 5 out of 5 by from Deng Deng, L. et al. (PubMed 26278136) reported that Histamine deficiency exacerbates myocardial injury in acute myocardial infarction through impaired macrophage infiltration and increased cardiomyocyte apoptosis. -SCBT Publication Review
Date published: 2015-01-18
  • y_2019, m_11, d_15, h_20
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.2
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_202650, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 42ms
  • REVIEWS, PRODUCT

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.