Herbimycin CA minor analog of herbimycin complex

Herbimycin C (CAS 91700-92-4)

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Application: A minor analog of herbimycin complex
CAS Number: 91700-92-4
Purity: >98%
Molecular Weight: 560.64
Molecular Formula: C29H40N2O9
* Refer to Certificate of Analysis for lot specific data (including water content).
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Herbimycin C is a minor analogue of herbimycin complex isolated from Streptomyces hygroscopicus. Herbimycin C possesses potent antitumor activity and has been shown to convert Rous sarcoma virus- infected rat kidney cells into normal cells. Research on related metabolites, herbimycin A and geldanamycin has stimulated intensive interest in this class as selective antitumor agents and for the prolonging the viability of tissue-cultured cells and organs.


References

1. Shibata K., et al. 1986. J. Antibiot. 39: 1630-1633. PMID: 3793634
2. Uehara Y. 2003. Curr. Cancer Drug Targets. 3: 325-230. PMID: 14529384

Physical State :
Solid
Derived From :
Streptomyces sp.
Solubility :
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
6438544
SMILES :
CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C=C(C1OC)C2=O)C)OC)OC(=O)N)C)C)O)OC

Download SDS (MSDS)

Certificate of Analysis

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