Haloperidol Antibody (7001): sc-66046

Haloperidol Antibody (7001) is a mouse monoclonal IgG1 antibody that detects Haloperidol protein of non-species reactive by enzyme-linked immunosorbent assay (ELISA). Anti-Haloperidol antibody (7001) is available as a non-conjugated monoclonal isotype antibody, providing researchers with a reliable tool for studying this important neuroleptic drug. Haloperidol, known by various names such as Aloperidin, Brotopon, and Dozic, is a butyrophenone antipsychotic that plays a crucial role in treating severe psychiatric conditions, including schizophrenia and acute psychotic states. Haloperidol′s function involves blocking dopamine receptors in the limbic system and mesocortex, which is vital for mitigating symptoms associated with dopaminergic overactivity in the brain. This mechanism helps restore motor coordination and serves as an effective intervention for mania, agitation, chronic pain, and chemotherapy-induced nausea. Despite showing over 50 times more potency than similar medications, Haloperidol can cause side effects, including constipation, dry mouth, hypotension, sedation, and lactation in both sexes. Anti-Haloperidol antibody (7001) represents an essential resource for researchers exploring the multifaceted roles of this drug in clinical settings and interactions within the neuropharmacological landscape.

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Haloperidol Antibody (7001) References:

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2. Effects of chronic haloperidol and clozapine treatment on neurogenesis in the adult rat hippocampus.  |  Halim, ND., et al. 2004. Neuropsychopharmacology. 29: 1063-9. PMID: 15010699
3. Haloperidol versus chlorpromazine for schizophrenia.  |  Leucht, C., et al. 2008. Cochrane Database Syst Rev. CD004278. PMID: 18254045
4. Haloperidol regulates the phosphorylation level of the MEK-ERK-p90RSK signal pathway via protein phosphatase 2A in the rat frontal cortex.  |  Kim, SH., et al. 2008. Int J Neuropsychopharmacol. 11: 509-17. PMID: 18272021
5. Haloperidol versus ondansetron for prophylaxis of postoperative nausea and vomiting.  |  Rosow, CE., et al. 2008. Anesth Analg. 106: 1407-9, table of contents. PMID: 18420852
6. Olanzapine, but not haloperidol, enhances PSA-NCAM immunoreactivity in rat prefrontal cortex.  |  Frasca, A., et al. 2008. Int J Neuropsychopharmacol. 11: 591-5. PMID: 18593508
7. Haloperidol both prevents and reverses quinpirole-induced nonregulatory water intake, a putative animal model of psychogenic polydipsia.  |  Amato, D., et al. 2008. Psychopharmacology (Berl). 200: 157-65. PMID: 18597076
8. Clozapine or Haloperidol in rats prenatally exposed to methylazoxymethanol, a compound inducing entorhinal-hippocampal deficits, alter brain and blood neurotrophins' concentrations.  |  Fiore, M., et al. 2008. Ann Ist Super Sanita. 44: 167-77. PMID: 18660566
9. Dopamine inhibits mitochondrial motility in hippocampal neurons.  |  Chen, S., et al. 2008. PLoS One. 3: e2804. PMID: 18665222
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