HADHSC Antibody (A-5) is a mouse monoclonal IgG2a (kappa light chain) provided at 200 µg/ml
raised against amino acids 151-314 mapping at the C-terminus of HADHSC of human origin
HADHSC Antibody (A-5) is recommended for detection of HADHSC of mouse, rat and human origin by WB, IP, IF and ELISA
HADHSC Antibody (A-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of HADHSC (A-5): sc-376525.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
HADHSC (hydroxyacyl-Coenzyme A (CoA) dehydrogenase, short chain), also known as HAD, HHF4, HADH1, SCHAD or M/SCHAD (Medium and short chain L-3-hydroxyacyl-CoA dehydrogenase), is a mitochondrial matrix protein expressed in pancreas, liver, heart, kidney and skeletal muscle. HADHSC exists as a homodimer that participates in lipid metabolism and is essential for the β-oxidation of medium and short chain fatty acids. More specifically, HADHSC catalyzes the dehydrogenation of 3-hydroxyacyl-CoAs to their corresponding 3-ketoacyl-CoAs while NAD+ is simultaneously reduced to NADH. Defects in HADHSC can lead to HADH (3-α-hydroxyacyl-CoA dehydrogenase) deficiency and familial hyperinsulinemic hypoglycemia 4 (HHF4). HADH deficiency is characterized as a metabolic disorder with patients exhibiting hepatoencephalopathy, hypoglycemia, myopathy or cardiomyopathy and sometimes experiencing sudden death. HHF4 is a disorder characterized by elevated insulin secretion that, if left untreated, can cause brain damage from recurrent hypoglycemia episodes.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences